Preclinical evaluation of tyrosine kinase 2 inhibitors for human beta-cell protection in type 1 diabetes

AIM: Type 1 diabetes (T1D) is a chronic autoimmune disease leading to progressive loss of pancreatic beta cells. Interferon (IFN)-α plays a critical role in the crosstalk between pancreatic beta cells and the immune system in early insulitis. In human beta cells IFNα signals through JAK1 and TYK2, l...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Diabetes Obes Metab
Autors principals: de Brachène, Alexandra Coomans, Castela, Angela, de Beeck, Anne Op, Mirmira, Raghavendra G., Marselli, Lorella, Marchetti, Piero, Masse, Craig, Miao, Wenyan, Leit, Silvana, Evans-Molina, Carmella, Eizirik, Decio L.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080968/
https://ncbi.nlm.nih.gov/pubmed/32476252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.14104
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars