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Ryk modulates the niche activity of mesenchymal stromal cells by fine-tuning canonical Wnt signaling

The importance of modulating the intensity of Wnt signaling has been highlighted in various biological models, but their mechanisms remain unclear. In this study, we found that Ryk—an atypical Wnt receptor with a pseudokinase domain—has a Wnt-modulating effect in bone marrow stromal cells to control...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Jeong, Seon-Yeong, Lyu, Jungmook, Kim, Jin-A, Oh, Il-Hoan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080773/
https://ncbi.nlm.nih.gov/pubmed/32724069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0477-y
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