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Ryk modulates the niche activity of mesenchymal stromal cells by fine-tuning canonical Wnt signaling
The importance of modulating the intensity of Wnt signaling has been highlighted in various biological models, but their mechanisms remain unclear. In this study, we found that Ryk—an atypical Wnt receptor with a pseudokinase domain—has a Wnt-modulating effect in bone marrow stromal cells to control...
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| Veröffentlicht in: | Exp Mol Med |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8080773/ https://ncbi.nlm.nih.gov/pubmed/32724069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0477-y |
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