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Ryk modulates the niche activity of mesenchymal stromal cells by fine-tuning canonical Wnt signaling

The importance of modulating the intensity of Wnt signaling has been highlighted in various biological models, but their mechanisms remain unclear. In this study, we found that Ryk—an atypical Wnt receptor with a pseudokinase domain—has a Wnt-modulating effect in bone marrow stromal cells to control...

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Publicat a:Exp Mol Med
Autors principals: Jeong, Seon-Yeong, Lyu, Jungmook, Kim, Jin-A, Oh, Il-Hoan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080773/
https://ncbi.nlm.nih.gov/pubmed/32724069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-020-0477-y
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