Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy

The heterogeneous pathobiology underlying Ulcerative Colitis (UC) is not fully understood. Using publicly available transcriptomes from adult UC patients, we identified the immune cell landscape, molecular pathways, and differentially expressed genes (DEGs) across patient cohorts and their associati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Penrose, Harrison M., Iftikhar, Rida, Collins, Morgan E., Toraih, Eman, Ruiz, Emmanuelle, Ungerleider, Nathan, Nakhoul, Hani, Flemington, Erik F., Kandil, Emad, Shah, Shamita B., Savkovic, Suzana D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079702/
https://ncbi.nlm.nih.gov/pubmed/33907256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88489-w
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