Neutron reflectometry and NMR spectroscopy of full-length Bcl-2 protein reveal its membrane localization and conformation

B-cell lymphoma 2 (Bcl-2) proteins are the main regulators of mitochondrial apoptosis. Anti-apoptotic Bcl-2 proteins possess a hydrophobic tail-anchor enabling them to translocate to their target membrane and to shift into an active conformation where they inhibit pro-apoptotic Bcl-2 proteins to ens...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Mushtaq, Ameeq Ul, Ådén, Jörgen, Clifton, Luke A., Wacklin-Knecht, Hanna, Campana, Mario, Dingeldein, Artur P. G., Persson, Cecilia, Sparrman, Tobias, Gröbner, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079415/
https://ncbi.nlm.nih.gov/pubmed/33907308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02032-1
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados