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Nucleic Acid-Based Drug Delivery Strategies

Nucleic acids have not been widely considered as an optimal material for drug delivery. Indeed, unmodified nucleic acids are enzymatically unstable, too hydrophilic for cell uptake and payload encapsulation, and may cause unintended biological responses such as immune system activation and prolongat...

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Библиографические подробности
Опубликовано в: :J Control Release
Главные авторы: Tan, Xuyu, Jia, Fei, Wang, Ping, Zhang, Ke
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079167/
https://ncbi.nlm.nih.gov/pubmed/32272123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.03.040
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