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Formulation of a Peptide Nucleic Acid Based Nucleic Acid Delivery Construct
Gene delivery biomaterials need to be designed to efficiently achieve nuclear delivery of plasmid DNA. Polycations have been used to package DNA and other nucleic acids within sub-micron sized particles, offering protection from shear-induced or enzymatic degradation. However, cytotoxicity issues co...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891923/ https://ncbi.nlm.nih.gov/pubmed/20131756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900328j |
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