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Formulation of pH responsive peptides as inhalable dry powders for pulmonary delivery of nucleic acids

Nucleic acids have the potential to be used as therapies or vaccines for many different types of disease but delivery remains the most significant challenge to their clinical adoption. pH responsive peptides containing either histidine or derivatives of 2,3-diaminopropionic acid (Dap) can mediate ef...

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Detalhes bibliográficos
Main Authors: Liang, Wanling, Kwok, Philip C.L., Chow, Michael Y.T., Tang, Patricia, Mason, A. James, Chan, Hak-Kim, Lam, Jenny. K.W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948054/
https://ncbi.nlm.nih.gov/pubmed/23702276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2013.05.006
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