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Heat-Stable Dry Powder Oxytocin Formulations for Delivery by Oral Inhalation

In this work, heat stable dry powders of oxytocin (OT) suitable for delivery by oral inhalation were prepared. The OT dry powders were prepared by spray drying using excipients chosen to promote OT stability including trehalose, isoleucine, polyvinylpyrrolidone, citrate (sodium citrate and citric ac...

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Detalles Bibliográficos
Publicado en:AAPS PharmSciTech
Main Authors: Fabio, Karine, Curley, Kieran, Guarneri, Joseph, Adamo, Benoit, Laurenzi, Brendan, Grant, Marshall, Offord, Robin, Kraft, Kelly, Leone-Bay, Andrea
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666249/
https://ncbi.nlm.nih.gov/pubmed/25776985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0314-0
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