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Heat-Stable Dry Powder Oxytocin Formulations for Delivery by Oral Inhalation

In this work, heat stable dry powders of oxytocin (OT) suitable for delivery by oral inhalation were prepared. The OT dry powders were prepared by spray drying using excipients chosen to promote OT stability including trehalose, isoleucine, polyvinylpyrrolidone, citrate (sodium citrate and citric ac...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Fabio, Karine, Curley, Kieran, Guarneri, Joseph, Adamo, Benoit, Laurenzi, Brendan, Grant, Marshall, Offord, Robin, Kraft, Kelly, Leone-Bay, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666249/
https://ncbi.nlm.nih.gov/pubmed/25776985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0314-0
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