Heat-Stable Dry Powder Oxytocin Formulations for Delivery by Oral Inhalation

In this work, heat stable dry powders of oxytocin (OT) suitable for delivery by oral inhalation were prepared. The OT dry powders were prepared by spray drying using excipients chosen to promote OT stability including trehalose, isoleucine, polyvinylpyrrolidone, citrate (sodium citrate and citric ac...

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Dettagli Bibliografici
Pubblicato in:AAPS PharmSciTech
Autori principali: Fabio, Karine, Curley, Kieran, Guarneri, Joseph, Adamo, Benoit, Laurenzi, Brendan, Grant, Marshall, Offord, Robin, Kraft, Kelly, Leone-Bay, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666249/
https://ncbi.nlm.nih.gov/pubmed/25776985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0314-0
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