Spray freeze drying of small nucleic acids as inhaled powder for pulmonary delivery

The therapeutic potential of small nucleic acids such as small interfering RNA (siRNA) to treat lung diseases has been successfully demonstrated in many in vivo studies. A major barrier to their clinical application is the lack of a safe and efficient inhaled formulation. In this study, spray freeze...

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Bibliografiska uppgifter
I publikationen:Asian J Pharm Sci
Huvudupphovsmän: Liang, Wanling, Chan, Alan Y.L., Chow, Michael Y.T., Lo, Fiona F.K., Qiu, Yingshan, Kwok, Philip C.L., Lam, Jenny K.W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Shenyang Pharmaceutical University 2018
Ämnen:
Original Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032260/
https://ncbi.nlm.nih.gov/pubmed/32104389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2017.10.002
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