Spray freeze drying of small nucleic acids as inhaled powder for pulmonary delivery

The therapeutic potential of small nucleic acids such as small interfering RNA (siRNA) to treat lung diseases has been successfully demonstrated in many in vivo studies. A major barrier to their clinical application is the lack of a safe and efficient inhaled formulation. In this study, spray freeze...

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Bibliografische gegevens
Gepubliceerd in:Asian J Pharm Sci
Hoofdauteurs: Liang, Wanling, Chan, Alan Y.L., Chow, Michael Y.T., Lo, Fiona F.K., Qiu, Yingshan, Kwok, Philip C.L., Lam, Jenny K.W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Shenyang Pharmaceutical University 2018
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Original Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032260/
https://ncbi.nlm.nih.gov/pubmed/32104389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2017.10.002
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