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Nucleic Acid-Based Drug Delivery Strategies

Nucleic acids have not been widely considered as an optimal material for drug delivery. Indeed, unmodified nucleic acids are enzymatically unstable, too hydrophilic for cell uptake and payload encapsulation, and may cause unintended biological responses such as immune system activation and prolongat...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Tan, Xuyu, Jia, Fei, Wang, Ping, Zhang, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079167/
https://ncbi.nlm.nih.gov/pubmed/32272123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2020.03.040
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