Synergy and allostery in ligand binding by HIV-1 Nef

The Nef protein of human and simian immunodeficiency viruses boosts viral pathogenicity through its interactions with host cell proteins. By combining the polyvalency of its large unstructured regions with the binding selectivity and strength of its folded core domain, Nef can associate with many di...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem J
Prif Awduron: Aldehaiman, Abdullah, Momin, Afaque A., Restouin, Audrey, Wang, Luyao, Shi, Xiaoli, Aljedani, Safia, Opi, Sandrine, Lugari, Adrien, Shahul Hameed, Umar F., Ponchon, Luc, Morelli, Xavier, Huang, Mingdong, Dumas, Christian, Collette, Yves, Arold, Stefan T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Portland Press Ltd. 2021
Pynciau:
Structural Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079166/
https://ncbi.nlm.nih.gov/pubmed/33787846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20201002
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