Synergy and allostery in ligand binding by HIV-1 Nef

The Nef protein of human and simian immunodeficiency viruses boosts viral pathogenicity through its interactions with host cell proteins. By combining the polyvalency of its large unstructured regions with the binding selectivity and strength of its folded core domain, Nef can associate with many di...

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Detalles Bibliográficos
Publicado en:Biochem J
Main Authors: Aldehaiman, Abdullah, Momin, Afaque A., Restouin, Audrey, Wang, Luyao, Shi, Xiaoli, Aljedani, Safia, Opi, Sandrine, Lugari, Adrien, Shahul Hameed, Umar F., Ponchon, Luc, Morelli, Xavier, Huang, Mingdong, Dumas, Christian, Collette, Yves, Arold, Stefan T.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2021
Assuntos:
Structural Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079166/
https://ncbi.nlm.nih.gov/pubmed/33787846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20201002
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