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GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo

Following fertilization, the genomes of the germ cells are reprogrammed to form the totipotent embryo. Pioneer transcription factors are essential for remodeling the chromatin and driving the initial wave of zygotic gene expression. In Drosophila melanogaster, the pioneer factor Zelda is essential f...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Gaskill, Marissa M, Gibson, Tyler J, Larson, Elizabeth D, Harrison, Melissa M
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079149/
https://ncbi.nlm.nih.gov/pubmed/33720012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66668
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