Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos

The regulation of transcription requires the coordination of numerous activities on DNA, yet how transcription factors mediate these activities remains poorly understood. Here, we use lattice light-sheet microscopy to integrate single-molecule and high-speed 4D imaging in developing Drosophila embry...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Mir, Mustafa, Stadler, Michael R, Ortiz, Stephan A, Hannon, Colleen E, Harrison, Melissa M, Darzacq, Xavier, Eisen, Michael B
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
Assuntos:
Chromosomes and Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307861/
https://ncbi.nlm.nih.gov/pubmed/30589412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40497
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