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Dynamic multifactor hubs interact transiently with sites of active transcription in Drosophila embryos

The regulation of transcription requires the coordination of numerous activities on DNA, yet how transcription factors mediate these activities remains poorly understood. Here, we use lattice light-sheet microscopy to integrate single-molecule and high-speed 4D imaging in developing Drosophila embry...

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書目詳細資料
發表在:eLife
Main Authors: Mir, Mustafa, Stadler, Michael R, Ortiz, Stephan A, Hannon, Colleen E, Harrison, Melissa M, Darzacq, Xavier, Eisen, Michael B
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307861/
https://ncbi.nlm.nih.gov/pubmed/30589412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40497
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