GAF is essential for zygotic genome activation and chromatin accessibility in the early Drosophila embryo

Following fertilization, the genomes of the germ cells are reprogrammed to form the totipotent embryo. Pioneer transcription factors are essential for remodeling the chromatin and driving the initial wave of zygotic gene expression. In Drosophila melanogaster, the pioneer factor Zelda is essential f...

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Udgivet i:eLife
Main Authors: Gaskill, Marissa M, Gibson, Tyler J, Larson, Elizabeth D, Harrison, Melissa M
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2021
Fag:
Chromosomes and Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079149/
https://ncbi.nlm.nih.gov/pubmed/33720012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66668
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