mtDNA depletion-like syndrome in Wilson disease

BACKGROUND & AIMS: Wilson disease is caused by mutations in the copper transporter ATP7B, with its main pathology attributed to copper-mediated oxidative damage. The limited therapeutic effect of copper chelators and the early occurrence of mitochondrial deficits, however, undermine the prevalen...

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發表在:Liver Int
Main Authors: Medici, Valentina, Sarode, Gaurav Vilas, Napoli, Eleonora, Song, Gyu-Young, Shibata, Noreene M., Guimarães, Andre Oliveira, Mordaunt, Charles E., Kieffer, Dorothy A., Mazi, Tagreed A., Czlonkowska, Anna, Litwin, Tomasz, LaSalle, Janine M., Giulivi, Cecilia
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8079140/
https://ncbi.nlm.nih.gov/pubmed/32996699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14646
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