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Function of Multidrug Resistance Transporters is Disrupted by Infection Mimics in Human Brain Endothelial Cells
P-glycoprotein (P-gp/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) modulate the distribution of drugs and toxins across the blood-brain barrier (BBB). Animal studies reported that infection-induced disruption of these transporters in the developing BBB impairs fetal brain protection. Howe...
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| I publikationen: | Tissue Barriers |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Taylor & Francis
2021
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8078541/ https://ncbi.nlm.nih.gov/pubmed/33427563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21688370.2020.1860616 |
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