Targeting the HTLV-I-Regulated BATF3/IRF4 Transcriptional Network in Adult T Cell Leukemia/Lymphoma

Adult T cell leukemia/lymphoma (ATLL) is a frequently incurable disease associated with the human lymphotropic virus type I (HTLV-I). RNAi screening of ATLL lines revealed that their proliferation depends on BATF3 and IRF4, which cooperatively drive ATLL-specific gene expression. HBZ, the only HTLV-...

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Publicado no:Cancer Cell
Main Authors: Nakagawa, Masao, Shaffer, Arthur L., Ceribelli, Michele, Zhang, Meili, Wright, George, Huang, Da Wei, Xiao, Wenming, Powell, John, Petrus, Michael N., Yang, Yibin, Phelan, James D., Kohlhammer, Holger, Dubois, Sigrid P., Yoo, Hee Min, Bachy, Emmanuel, Webster, Daniel E., Yang, Yandan, Xu, Weihong, Yu, Xin, Zhao, Hong, Bryant, Bonita R., Shimono, Joji, Ishio, Takashi, Maeda, Michiyuki, Green, Patrick L., Waldmann, Thomas A., Staudt, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078141/
https://ncbi.nlm.nih.gov/pubmed/30057145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.06.014
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