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Rapid decay of host basal mRNAs during SARS-CoV-2 infection perturbs host antiviral mRNA biogenesis and export

A key feature of the mammalian innate immune response to viral infection is the transcriptional induction of interferon (IFN) genes, which encode for secreted proteins that prime the antiviral response and limit viral replication and dissemination. A hallmark of severe COVID-19 disease caused by SAR...

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Podrobná bibliografie
Vydáno v:bioRxiv
Hlavní autoři: Burke, James M., St Clair, Laura A., Perera, Rushika, Parker, Roy
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8077573/
https://ncbi.nlm.nih.gov/pubmed/33907748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.04.19.440452
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