The Wdr1-LIMK-Cofilin Axis Controls B Cell Antigen Receptor-Induced Actin Remodeling and Signaling at the Immune Synapse

When B cells encounter membrane-bound antigens, the formation and coalescence of B cell antigen receptor (BCR) microclusters amplifies BCR signaling. The ability of B cells to probe the surface of antigen-presenting cells (APCs) and respond to APC-bound antigens requires remodeling of the actin cyto...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Bolger-Munro, Madison, Choi, Kate, Cheung, Faith, Liu, Yi Tian, Dang-Lawson, May, Deretic, Nikola, Keane, Connor, Gold, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076898/
https://ncbi.nlm.nih.gov/pubmed/33928084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.649433
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