Visualizing the Actin and Microtubule Cytoskeletons at the B-cell Immune Synapse Using Stimulated Emission Depletion (STED) Microscopy

B cells that bind to membrane-bound antigens (e.g., on the surface of an antigen-presenting cell) form an immune synapse, a specialized cellular structure that optimizes B-cell receptor (BCR) signaling and BCR-mediated antigen acquisition. Both the remodeling of the actin cytoskeleton and the reorie...

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Udgivet i:J Vis Exp
Main Authors: Wang, Jia C., Bolger-Munro, Madison, Gold, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2018
Fag:
Immunology and Infection
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933440/
https://ncbi.nlm.nih.gov/pubmed/29683438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57028
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