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A Perspective on Accelerated Aging Caused by the Genetic Deficiency of the Metabolic Protein, OPA1

Autosomal Dominant Optic Atrophy (ADOA) is an ophthalmological condition associated primarily with mutations in the OPA1 gene. It has variable onset, sometimes juvenile, but in other patients, the disease does not manifest until adult middle age despite the presence of a pathological mutation. Thus,...

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Détails bibliographiques
Publié dans:Front Neurol
Auteurs principaux: Erchova, Irina, Sun, Shanshan, Votruba, Marcela
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076550/
https://ncbi.nlm.nih.gov/pubmed/33927681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.641259
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