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A Perspective on Accelerated Aging Caused by the Genetic Deficiency of the Metabolic Protein, OPA1

Autosomal Dominant Optic Atrophy (ADOA) is an ophthalmological condition associated primarily with mutations in the OPA1 gene. It has variable onset, sometimes juvenile, but in other patients, the disease does not manifest until adult middle age despite the presence of a pathological mutation. Thus,...

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Detalles Bibliográficos
Publicado en:Front Neurol
Main Authors: Erchova, Irina, Sun, Shanshan, Votruba, Marcela
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076550/
https://ncbi.nlm.nih.gov/pubmed/33927681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.641259
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