OPA1 deficiency accelerates hippocampal synaptic remodelling and age-related deficits in learning and memory

A healthy mitochondrial network is essential for the maintenance of neuronal synaptic integrity. Mitochondrial and metabolic dysfunction contributes to the pathogenesis of many neurodegenerative diseases including dementia. OPA1 is the master regulator of mitochondrial fusion and fission and is like...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Brain Commun
Egile Nagusiak: Bevan, Ryan J, Williams, Pete A, Waters, Caroline T, Thirgood, Rebecca, Mui, Amanda, Seto, Sharon, Good, Mark, Morgan, James E, Votruba, Marcela, Erchova, Irina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2020
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566495/
https://ncbi.nlm.nih.gov/pubmed/33094281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcaa101
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