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Use of omeprazole, the proton pump inhibitor, as a potential therapy for the capecitabine-induced hand-foot syndrome

Hand-foot syndrome (HFS), also known as palmar-plantar erythrodysesthesia (PPE), is a major side effect of capecitabine. Although the pathogenesis of HFS remains unknown, some studies suggested a potential involvement of inflammation in its pathogenesis. Proton pump inhibitors (PPIs) have been repor...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Hiromoto, Shiori, Kawashiri, Takehiro, Yamanaka, Natsumi, Kobayashi, Daisuke, Mine, Keisuke, Inoue, Mizuki, Uchida, Mayako, Shimazoe, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076322/
https://ncbi.nlm.nih.gov/pubmed/33903667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88460-9
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