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Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury

BACKGROUND: The administration of supplemental oxygen to treat ventilatory insufficiency may lead to the formation of reactive oxygen species and subsequent tissue damage. Cytochrome P4501A1 (CYP1A1) can modulate hyperoxic lung injury by a currently unknown mechanism. Our objective was to evaluate t...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Richter, Jute, Jimenez, Julio, Nagatomo, Taro, Toelen, Jaan, Brady, Paul, Salaets, Thomas, Lesage, Flore, Vanoirbeek, Jeroen, Deprest, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002203/
https://ncbi.nlm.nih.gov/pubmed/27567616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1009-3
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