Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury

BACKGROUND: The administration of supplemental oxygen to treat ventilatory insufficiency may lead to the formation of reactive oxygen species and subsequent tissue damage. Cytochrome P4501A1 (CYP1A1) can modulate hyperoxic lung injury by a currently unknown mechanism. Our objective was to evaluate t...

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Bibliografske podrobnosti
izdano v:J Transl Med
Main Authors: Richter, Jute, Jimenez, Julio, Nagatomo, Taro, Toelen, Jaan, Brady, Paul, Salaets, Thomas, Lesage, Flore, Vanoirbeek, Jeroen, Deprest, Jan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002203/
https://ncbi.nlm.nih.gov/pubmed/27567616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1009-3
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