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Functional modulation of phosphodiesterase-6 by calcium in mouse rod photoreceptors

Phosphodiesterase-6 (PDE6) is a key protein in the G-protein cascade converting photon information to bioelectrical signals in vertebrate photoreceptor cells. Here, we demonstrate that PDE6 is regulated by calcium, contrary to the common view that PDE1 is the unique PDE class whose activity is modul...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Turunen, Teemu, Koskelainen, Ari
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076185/
https://ncbi.nlm.nih.gov/pubmed/33903621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88140-8
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