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Functional modulation of phosphodiesterase-6 by calcium in mouse rod photoreceptors

Phosphodiesterase-6 (PDE6) is a key protein in the G-protein cascade converting photon information to bioelectrical signals in vertebrate photoreceptor cells. Here, we demonstrate that PDE6 is regulated by calcium, contrary to the common view that PDE1 is the unique PDE class whose activity is modul...

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Sonraí Bibleagrafaíochta
Foilsithe in:Sci Rep
Main Authors: Turunen, Teemu, Koskelainen, Ari
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8076185/
https://ncbi.nlm.nih.gov/pubmed/33903621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88140-8
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