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Functional modulation of phosphodiesterase-6 by calcium in mouse rod photoreceptors
Phosphodiesterase-6 (PDE6) is a key protein in the G-protein cascade converting photon information to bioelectrical signals in vertebrate photoreceptor cells. Here, we demonstrate that PDE6 is regulated by calcium, contrary to the common view that PDE1 is the unique PDE class whose activity is modul...
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| Publicado en: | Sci Rep |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8076185/ https://ncbi.nlm.nih.gov/pubmed/33903621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88140-8 |
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