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Tissue-Engineering the Fibrous Pancreatic Tumour Stroma Capsule in 3D Tumouroids to Demonstrate Paclitaxel Response

Pancreatic cancer is a unique cancer in that up to 90% of its tumour mass is composed of a hypovascular and fibrotic stroma. This makes it extremely difficult for chemotherapies to be delivered into the core of the cancer mass. We tissue-engineered a biomimetic 3D pancreatic cancer (“tumouroid”) mod...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Pape, Judith, Stamati, Katerina, Al Hosni, Rawiya, Uchegbu, Ijeoma F., Schatzlein, Andreas G., Loizidou, Marilena, Emberton, Mark, Cheema, Umber
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074746/
https://ncbi.nlm.nih.gov/pubmed/33924238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084289
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