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3D Cancer Models: The Need for a Complex Stroma, Compartmentalization and Stiffness

The use of tissue-engineered 3D models of cancer has grown in popularity with recent advances in the field of cancer research. 3D models are inherently more biomimetic compared to 2D cell monolayers cultured on tissue-culture plastic. Nevertheless 3D models still lack the cellular and matrix complex...

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Detalles Bibliográficos
Publicado en:Front Bioeng Biotechnol
Main Authors: Pape, Judith, Emberton, Mark, Cheema, Umber
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072339/
https://ncbi.nlm.nih.gov/pubmed/33912551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.660502
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