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The anti-angiogenic tyrosine kinase inhibitor Pazopanib kills cancer cells and disrupts endothelial networks in biomimetic three-dimensional renal tumouroids

Pazopanib is a tyrosine kinase inhibitor used to treat renal cell carcinoma. Few in vitro studies investigate its effects towards cancer cells or endothelial cells in the presence of cancer. We tested the effect of Pazopanib on renal cell carcinoma cells (CAKI-2,786-O) in two-dimensional and three-d...

詳細記述

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書誌詳細
出版年:J Tissue Eng
主要な著者: Stamati, Katerina, Redondo, Patricia A, Nyga, Agata, Neves, Joana B, Tran, Maxine GB, Emberton, Mark, Cheema, Umber, Loizidou, Marilena
フォーマット: Artigo
言語:Inglês
出版事項: SAGE Publications 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238304/
https://ncbi.nlm.nih.gov/pubmed/32489578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2041731420920597
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