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Relationship between Oxidative Stress and Imatinib Resistance in Model Chronic Myeloid Leukemia Cells
Chronic myeloid leukemia (CML) develops due to the presence of the BCR-ABL1 protein, a target of tyrosine kinase inhibitors (TKIs), such as imatinib (IM), used in a CML therapy. CML eradication is a challenge due to developing resistance to TKIs. BCR-ABL1 induces endogenous oxidative stress leading...
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| Publicado no: | Biomolecules |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8074285/ https://ncbi.nlm.nih.gov/pubmed/33924068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040610 |
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