Central Alteration in Peripheral Neuropathy of Trembler-J Mice: Hippocampal pmp22 Expression and Behavioral Profile in Anxiety Tests

Charcot–Marie–Tooth (CMT) type 1 disease is the most common human hereditary demyelinating neuropathy. Mutations in pmp22 cause about 70% of all CMT1. Trembler-J (TrJ/+) mice are an animal model of CMT1E, having the same spontaneous pmp22 mutation that is found in humans. We compared the behavior pr...

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Vydáno v:Biomolecules
Hlavní autoři: Damián, Juan Pablo, Vázquez Alberdi, Lucia, Canclini, Lucía, Rosso, Gonzalo, Bravo, Silvia Olivera, Martínez, Mariana, Uriarte, Natalia, Ruiz, Paul, Calero, Miguel, Di Tomaso, María Vittoria, Kun, Alejandra
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074002/
https://ncbi.nlm.nih.gov/pubmed/33921657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040601
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