Laddar...

The Peripheral Neuropathy-Linked Trembler and Trembler-J Mutant Forms of Peripheral Myelin Protein 22 are Folding-Destabilized

Dominant mutations in the tetraspan membrane protein peripheral myelin protein 22 (PMP22) are known to result in peripheral neuropathies such as Charcot-Marie-Tooth Type 1A (CMT1A) disease via mechanisms that appear to be closely linked to misfolding of PMP22 in the membrane of the endoplasmic retic...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Myers, Jeffrey K., Mobley, Charles K., Sanders, Charles R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566783/
https://ncbi.nlm.nih.gov/pubmed/18795802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801157p
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!