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Transport of Trembler-J Mutant Peripheral Myelin Protein 22 Is Blocked in the Intermediate Compartment and Affects the Transport of the Wild-Type Protein by Direct Interaction

Peripheral myelin protein 22 (PMP22) is an integral membrane protein that is essential for the normal formation and maintenance of peripheral myelin. Duplications, deletions, or mutations in the PMP22 gene account for a set of dominantly inherited peripheral neuropathies. The heterozygous Trembler-J...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tobler, Andreas R., Notterpek, Lucia, Naef, Roland, Taylor, Verdon, Suter, Ueli, Shooter, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782545/
https://ncbi.nlm.nih.gov/pubmed/10066256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-06-02027.1999
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