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Chronic Administrations of Guanfacine on Mesocortical Catecholaminergic and Thalamocortical Glutamatergic Transmissions

It has been established that the selective α2A adrenoceptor agonist guanfacine reduces hyperactivity and improves cognitive impairment in patients with attention-deficit/hyperactivity disorder (ADHD). The major mechanisms of guanfacine are considered to involve the activation of the postsynaptic α2A...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Fukuyama, Kouji, Nakano, Tomosuke, Shiroyama, Takashi, Okada, Motohiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073983/
https://ncbi.nlm.nih.gov/pubmed/33923533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084122
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