Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence

Human aromatase is a member of the cytochrome P450 superfamily, involved in steroid hormones biosynthesis. In particular, it converts androgen into estrogens being therefore responsible for the correct sex steroids balance. Due to its capacity in producing estrogens it has also been considered as a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biol Direct
Hauptverfasser: Di Nardo, Giovanna, Di Venere, Almerinda, Zhang, Chao, Nicolai, Eleonora, Castrignanò, Silvia, Di Paola, Luisa, Gilardi, Gianfranco, Mei, Giampiero
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073906/
https://ncbi.nlm.nih.gov/pubmed/33902660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-021-00292-9
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