Polymorphism on human aromatase affects protein dynamics and substrate binding: spectroscopic evidence

Human aromatase is a member of the cytochrome P450 superfamily, involved in steroid hormones biosynthesis. In particular, it converts androgen into estrogens being therefore responsible for the correct sex steroids balance. Due to its capacity in producing estrogens it has also been considered as a...

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Detalhes bibliográficos
Publicado no:Biol Direct
Main Authors: Di Nardo, Giovanna, Di Venere, Almerinda, Zhang, Chao, Nicolai, Eleonora, Castrignanò, Silvia, Di Paola, Luisa, Gilardi, Gianfranco, Mei, Giampiero
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073906/
https://ncbi.nlm.nih.gov/pubmed/33902660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-021-00292-9
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