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Human Prostate Epithelial Cells Activate the AIM2 Inflammasome upon Cellular Senescence: Role of POP3 Protein in Aging-Related Prostatic Inflammation

Increased levels of type I (T1) interferon (IFN)-inducible POP3 protein in myeloid cells inhibit activation of the AIM2 inflammasome and production of IL-1β and IL-18 proinflammatory cytokines. The AIM2 mRNA levels were significantly higher in benign prostate hyperplasia (BPH) than the normal prosta...

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Bibliografiska uppgifter
I publikationen:Life (Basel)
Huvudupphovsmän: Panchanathan, Ravichandran, Ramalingam, Vaikundamoorthy, Liu, Hongzhu, Choubey, Divaker
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073538/
https://ncbi.nlm.nih.gov/pubmed/33923931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life11040366
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