Supervised enhancer prediction with epigenetic pattern recognition and targeted validation

Enhancers are important noncoding elements, but they have been traditionally hard to characterize experimentally. The development of massively parallel assays allows the characterization of large numbers of enhancers for the first time. Here, we developed a framework using Drosophila STARR-seq to cr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nat Methods
Hauptverfasser: Sethi, Anurag, Gu, Mengting, Gumusgoz, Emrah, Chan, Landon, Yan, Koon-Kiu, Rozowsky, Joel, Barozzi, Iros, Afzal, Veena, Akiyama, Jennifer A., Plajzer-Frick, Ingrid, Yan, Chengfei, Novak, Catherine S., Kato, Momoe, Garvin, Tyler H., Pham, Quan, Harrington, Anne, Mannion, Brandon J., Lee, Elizabeth A., Fukuda-Yuzawa, Yoko, Visel, Axel, Dickel, Diane E., Yip, Kevin Y., Sutton, Richard, Pennacchio, Len A., Gerstein, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073243/
https://ncbi.nlm.nih.gov/pubmed/32737473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-0907-8
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge