Genome-wide compendium and functional assessment of in vivo heart enhancers

Whole-genome sequencing is identifying growing numbers of non-coding variants in human disease studies, but the lack of accurate functional annotations prevents their interpretation. We describe the genome-wide landscape of distant-acting enhancers active in the developing and adult human heart, an...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Dickel, Diane E., Barozzi, Iros, Zhu, Yiwen, Fukuda-Yuzawa, Yoko, Osterwalder, Marco, Mannion, Brandon J., May, Dalit, Spurrell, Cailyn H., Plajzer-Frick, Ingrid, Pickle, Catherine S., Lee, Elizabeth, Garvin, Tyler H., Kato, Momoe, Akiyama, Jennifer A., Afzal, Veena, Lee, Ah Young, Gorkin, David U., Ren, Bing, Rubin, Edward M., Visel, Axel, Pennacchio, Len A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059478/
https://ncbi.nlm.nih.gov/pubmed/27703156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12923
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