Function-based Identification of Mammalian Enhancers Using Site-Specific Integration

The accurate and comprehensive identification of functional regulatory sequences in mammalian genomes remains a major challenge. Here we describe Site-specific Integration FACS-sequencing (SIF-seq), an unbiased, medium-throughput functional assay for the discovery of distant-acting enhancers. Plurip...

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Main Authors: Dickel, Diane E., Zhu, Yiwen, Nord, Alex S., Wylie, John N., Akiyama, Jennifer A., Afzal, Veena, Plajzer-Frick, Ingrid, Kirkpatrick, Aileen, Göttgens, Berthold, Bruneau, Benoit G., Visel, Axel, Pennacchio, Len A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008384/
https://ncbi.nlm.nih.gov/pubmed/24658141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2886
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