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Natural Compounds as Therapeutic Agents: The Case of Human Topoisomerase IB

Natural products are widely used as source for drugs development. An interesting example is represented by natural drugs developed against human topoisomerase IB, a ubiquitous enzyme involved in many cellular processes where several topological problems occur due the formation of supercoiled DNA. Hu...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Ottaviani, Alessio, Iacovelli, Federico, Fiorani, Paola, Desideri, Alessandro
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8073192/
https://ncbi.nlm.nih.gov/pubmed/33923641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084138
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