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The Challenges and Strategies of Antisense Oligonucleotide Drug Delivery

Antisense oligonucleotides (ASOs) are used to selectively inhibit the translation of disease-associated genes via Ribonuclease H (RNaseH)-mediated cleavage or steric hindrance. They are being developed as a novel and promising class of drugs targeting a wide range of diseases. Despite the great pote...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomedicines
Hauptverfasser: Gagliardi, Maria, Ashizawa, Ana Tari
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072990/
https://ncbi.nlm.nih.gov/pubmed/33923688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9040433
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