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The Challenges and Strategies of Antisense Oligonucleotide Drug Delivery
Antisense oligonucleotides (ASOs) are used to selectively inhibit the translation of disease-associated genes via Ribonuclease H (RNaseH)-mediated cleavage or steric hindrance. They are being developed as a novel and promising class of drugs targeting a wide range of diseases. Despite the great pote...
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| Veröffentlicht in: | Biomedicines |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8072990/ https://ncbi.nlm.nih.gov/pubmed/33923688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9040433 |
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