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Nanoparticle Delivery of Antisense Oligonucleotides and Their Application in the Exon Skipping Strategy for Duchenne Muscular Dystrophy

Antisense therapy is a powerful tool for inducing post-transcriptional modifications and thereby regulating target genes associated with disease. There are several classes of antisense oligonucleotides (AONs) with therapeutic use, such as double-stranded RNAs (interfering RNAs, utilized for gene sil...

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Autores principales: Falzarano, Maria Sofia, Passarelli, Chiara, Ferlini, Alessandra
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922138/
https://ncbi.nlm.nih.gov/pubmed/24506782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2013.0450
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