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Introduction of Cysteines in the Stalk Domain of Recombinant Influenza Virus N1 Neuraminidase Enhances Protein Stability and Immunogenicity in Mice

Influenza virus surface glycoproteins represent the main targets of the immune system during infection and vaccination. Current influenza virus vaccines rely mostly on the hemagglutinin, requiring a close match between the vaccine and circulating strains. Recently, the neuraminidase (NA) has become...

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Dades bibliogràfiques
Publicat a:Vaccines (Basel)
Autors principals: Strohmeier, Shirin, Carreño, Juan Manuel, Brito, Ruhi Nichalle, Krammer, Florian
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072926/
https://ncbi.nlm.nih.gov/pubmed/33921722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9040404
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