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Introduction of Cysteines in the Stalk Domain of Recombinant Influenza Virus N1 Neuraminidase Enhances Protein Stability and Immunogenicity in Mice

Influenza virus surface glycoproteins represent the main targets of the immune system during infection and vaccination. Current influenza virus vaccines rely mostly on the hemagglutinin, requiring a close match between the vaccine and circulating strains. Recently, the neuraminidase (NA) has become...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Vaccines (Basel)
Hauptverfasser: Strohmeier, Shirin, Carreño, Juan Manuel, Brito, Ruhi Nichalle, Krammer, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072926/
https://ncbi.nlm.nih.gov/pubmed/33921722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines9040404
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